There is happy news for those suffering from severe Treatment-Resistant Depression (TRD): Spravato (Esketamine) is a revolutionary medication that can bring relief from depressive episodes within hours. For the very first time in 60 yrs, we have a unique antidepressant treatment. For some patients, Spravato treatment is groundbreaking, allowing them to live a life free of depression.

What exactly is Spravato?

To begin, let us understand what Spravato is.  As a nasal spray, Spravato contains the drug “Esketamine” and is used in combination with oral antidepressants. It’s been demonstrated to benefit individuals with TRD as well as those having severe depression with suicidal ideation. Spravato is suitable for those who have tried two or more antidepressant prescription medicines by their doctor but have not noticed substantial relief.

What is Spravato (Esketamine) treatment like?

Spravato (Esketamine), like ketamine, really does have the tendency to distort your perception within the first 2 hours following treatment, therefore it must be taken in a clinical setting. Under the supervision of a doctor, take 3 doses of nasal spray, at 5-minute intervals. You will be monitored at the clinic under the supervision of a doctor until any potential adverse effects have subsided.

Spravato should be taken in combination with a standard antidepressant. The goal is for Spravato to offer immediate relief from depressive symptoms until the other medicine takes effect.

Is Spravato suitable for everyone?

Spravato is not for everyone. It is not recommended for adults with specific health complications. For those who have a history of aneurysms, for example, it is not advised that you take Spravato. Also, It is also not recommended for people who have had a history of brain hemorrhage or who are allergic to ketamine or esketamine. Working closely with a medical expert can help you figure out whether or not Spravato is suitable for you.

Who should consider taking Spravato Treatment?

Spravato is intended for adults suffering from Treatment-Resistant Depression (TRD)-  Depression unresponsive to at least 2 antidepressant medicines and for adults who have suicidal ideation with Major Depressive Disorder (MDD).

Spravato helps those who haven’t experienced progress with conventional antidepressants to feel what it’s like to be depressed-free. It offers patients hope that if they receive the right treatment, they will definitely feel much better.

How does Spravato Treat Depression?

Spravato functions differently than any of the other antidepressant medications. Antidepressant medicines that are often used raise levels of naturally occurring neurotransmitters in the brain like serotonin (monoamine neurotransmitter), noradrenaline, and dopamine. Such chemical messengers, also known as neurotransmitters, start and regulate brain cell-to-cell communication. Also, Chemical messengers control and influence our moods.

  • Serotonin is a neurotransmitter that modulates mood, anxiety, & happiness.
  • Norepinephrine improves our energy & focus levels. Norepinephrine outbursts can generate sensations of pleasure, but they can also promote high blood pressure & hyperactivity.
  • Dopamine, popularly known as a “feel-good” neurotransmitter and hormone, is responsible for the regulation of pleasure reward, contentment, and motivation.

People Suffering from Depression Experience Quick Relief

Antidepressants are often slow-acting. It might take many weeks for persons suffering from depression to see noticeable improvement. Sparavto (esketamine), on the other hand, has a quick effect on brain cells, providing relief from depression symptoms within hrs.

It’s Effective for Patients with TRD

Close to 33% of depressed people do not react to traditional antidepressants. Clinically, it’s proven that Spravato decreases depressive symptoms in the vast majority of patients. Also, Spravato does deliver results fast, sometimes as early as the first dosage. Conventional antidepressants might take weeks to function, giving people with TRD additional time to get agitated. 

Spravato Facilitates in the Formation of New Brain Connections

Untreated depression could cause severe brain damage and serve as a risk factor for dementia.  According to studies, depression patients showed a 20% shrinkage of the hippocampal, a part of the brain essential for memory/ remembrance and learning. However, spravato has the potential to mitigate the negative effects of depression.

If you think your depression medication isn’t working for TRD, speak with your doctor about Spravato Treatment.

Brain Spa is the very first REMS-certified Spavato treatment centre to provide Spravato for patients suffering from Treatment Resistant Depression (TRD), as well as a variety of other mental health treatments, like social anxiety disorder therapy.   

Are you ready to incorporate Spravato into your treatment plan? Contact Brain Spa right now. They can assist you through the procedure and we can help you determine how Spravato can assist with your TRD.

Feel free to contact us at 302 449 6601 or [email protected] for more information. Let’s get started on overcoming Treatment Resistant Depression (TRD).